Balkan Nephropathy: Evolution of Our Knowledge
نویسندگان
چکیده
منابع مشابه
The Balkan Nephropathy
This book attempts the awesome task of compiling a fairly complete bibliography of the clinical and experimental publications through 1964 on phenothiazines, butyrophenones, meprobamate "like" agents, and MAO inhibitors. Approximately two thirds of this book is bibliography with the remaining one third a narrative which is little more than an anotated bibliography. Both sections forsake critica...
متن کاملEndemic (Balkan) nephropathy is aristolochic acid nephropathy.
Endemic nephropathy is a syndrome that comprises two entities: chronic interstitial nephropathy and urothelial cell cancers predominantly of the upper urinary tract. The etiological agent for the disease is aristolochic acid, a compound found in the plants of Aristolochia spp. The development of urothelial cancers is characterized by the formation of aristolactam DNA adducts leading to mutation...
متن کاملOpen questions on Balkan nephropathy.
The prevalence of the disease was stable over many years, but now appears to decline in most affected settlements w1x. Some authors also suggest that the incidence of BEN decreases w1,2x and that it appears to be tapering off; others, however, describe a stable incidence of BEN w3x. The question arises on different epidemiological characteristics of the disease in different endemic regions. In ...
متن کاملEarly Screening of Balkan Endemic Nephropathy
Introduction Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical implementing of in-field screening of B...
متن کاملWeathered Coal Deposits and Balkan Endemic Nephropathy
The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
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ژورنال
عنوان ژورنال: American Journal of Kidney Diseases
سال: 2008
ISSN: 0272-6386
DOI: 10.1053/j.ajkd.2008.05.024